{"id":2905,"date":"2023-09-25T09:27:05","date_gmt":"2023-09-25T08:27:05","guid":{"rendered":"https:\/\/springerhealthcare.nl\/france\/?p=2905"},"modified":"2023-09-28T13:27:57","modified_gmt":"2023-09-28T12:27:57","slug":"see-how-stress-affects-inflammatory-bowel-disease","status":"publish","type":"post","link":"https:\/\/springerhealthplus.nl\/shmigrate\/see-how-stress-affects-inflammatory-bowel-disease\/","title":{"rendered":"See How Stress Affects Inflammatory Bowel Disease"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row full_width=&#8221;stretch_row&#8221; content_placement=&#8221;middle&#8221; css=&#8221;.vc_custom_1663187695627{padding-bottom: 37px !important;background-image: url(http:\/\/springerhealthcare.nl\/wp-content\/uploads\/sites\/24\/2022\/09\/science_connect_back.png?id=2486) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}&#8221; el_class=&#8221;sciencetitle&#8221;][vc_column][vc_custom_heading text=&#8221;Science Connect&#8221; font_container=&#8221;tag:h2|text_align:left|color:%23ffffff&#8221; use_theme_fonts=&#8221;yes&#8221; link=&#8221;url:https%3A%2F%2Fspringerhealthcare.nl%2Ffrance%2Fscience-connect-september-2023%2F&#8221;][vc_column_text css=&#8221;.vc_custom_1663186747780{margin-bottom: 40px !important;}&#8221;]<span style=\"color: #ffffff; font-size: 24px; line-height: 29px;\">A Springer Healthcare Initiative For Pharma Professionals<\/span>[\/vc_column_text][vc_column_text]<span style=\"color: #ee7d11; font-size: 28px; font-weight: 400; letter-spacing: 2px;\">SEPTEMBER 2023<br \/>\n<\/span>[\/vc_column_text][\/vc_column][\/vc_row][vc_row css=&#8221;.vc_custom_1538651642953{padding-top: 75px !important;}&#8221;][vc_column width=&#8221;3\/4&#8243; css=&#8221;.vc_custom_1538657061395{border-right-width: 1px !important;padding-top: 0px !important;border-right-color: #8faec1 !important;border-right-style: solid !important;}&#8221;][vc_custom_heading source=&#8221;post_title&#8221; font_container=&#8221;tag:h1|font_size:40px|text_align:left|line_height:60px&#8221; google_fonts=&#8221;font_family:Merriweather%3Aregular%2Citalic|font_style:700%20regular%3A700%3Anormal&#8221; el_class=&#8221;title&#8221; css=&#8221;.vc_custom_1664358136969{margin-bottom: 30px !important;}&#8221;][vc_column_text css=&#8221;.vc_custom_1686833173052{padding-bottom: 0px !important;}&#8221;]<span style=\"font-size: 18pt;\"><strong>In inflammatory bowel disease, mental stress can produce two painful responses<\/strong><\/span>[\/vc_column_text][vc_column_text el_class=&#8221;intro-box&#8221;]<span style=\"font-size: 16pt;\">By Josh Fischman, Now Medical Studios<\/span>[\/vc_column_text]<div class=\"thegem-te-post-featured-image featured-image--default featured-image--left hero-img thegem-custom-69f877b37f6959897\"> <div class=\"post-featured-image\"> <img src=\"https:\/\/springerhealthplus.nl\/shmigrate\/wp-content\/uploads\/sites\/24\/2023\/09\/2FEC464E-3CD9-4C05-BD88E8D8F2FA28B3_source.webp\" width=\"690\" height=\"479\" class=\"img-responsive\" alt=\"see-how-stress-affects-inflammatory-bowel-disease\" > <\/div> <\/div>[vc_column_text css=&#8221;.vc_custom_1689357004274{margin-bottom: 30px !important;}&#8221; el_class=&#8221;sc-img-caption&#8221;] Credit: Now Medical Studios[\/vc_column_text][vc_column_text]<p>Bouts of\u00a0<a href=\"https:\/\/www.cdc.gov\/ibd\/what-is-IBD.htm\" target=\"_blank\" rel=\"noopener\">disabling pain, bleeding, weight loss and hospitalization<\/a>\u00a0that sometimes require surgery: that&#8217;s the lot of about\u00a0<a href=\"https:\/\/www.cdc.gov\/mmwr\/volumes\/65\/wr\/mm6542a3.htm\" target=\"_blank\" rel=\"noopener\">three million adults<\/a>\u00a0in the U.S. who suffer from inflammatory bowel disease, or IBD. (The illness has two main forms, Crohn&#8217;s disease and ulcerative colitis. It is frequently associated with an\u00a0<a href=\"https:\/\/www.scientificamerican.com\/article\/the-terrible-toll-of-76-autoimmune-diseases\/\" target=\"_blank\" rel=\"noopener\">overactive immune system<\/a>\u00a0and may have a genetic component.) Treatments often involve some variety of immunosuppressant such as a steroid drug. But even controlled cases have periodic flare-ups, and the reasons have been hard to pin down.<\/p>\n<p>Now scientists have\u00a0<a href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(23)00475-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867423004750%3Fshowall%3Dtrue\" target=\"_blank\" rel=\"noopener\">traced two detailed molecular pathways from the brain to the gut<\/a>\u00a0that produce IBD flares. And in three different groups of IBD patients, they found that psychological stress\u2014a death in the family or a bad fight with a loved one, for instance\u2014can trigger the release of brain chemicals that cause IBD symptoms. This doesn&#8217;t mean IBD is all in the head, emphasizes Christoph A. Thaiss of the University of Pennsylvania, one of the researchers. But it does mean psychotherapy and targeted stress-management techniques have important\u2014and until now underappreciated\u2014roles to play in preventing and treating agonizing flares.<\/p>\n<figure data-responsive-image=\"responsive-image\">\n<div><img src=\"https:\/\/static.scientificamerican.com\/sciam\/assets\/Image\/2023\/saw0923Gsci31_d.jpg\" alt=\"Graphic shows how the release of a stress hormone from the brain can trigger IBD symptoms via two pathways in the gut, one leading to an inflammatory response and the other to impaired food movement.\" \/><\/div><figcaption><span style=\"line-height: 1.5em;font-size: 10pt\">Now Medical Studios; Source: \u201cThe Enteric Nervous System Relays Psychological Stress to Intestinal Inflammation,\u201d by Kai Markus Schneider et al., in\u00a0<em>Cell<\/em>, Vol. 186; June 22, 2023 (<em>reference<\/em>)<\/span><\/figcaption><\/figure>\n<section>\u00a0<\/section>\n<section>This article was originally published with the title &#8220;The Brain-Gut Connection&#8221; in Scientific American 329, 2, 86 (September 2023)doi:10.1038\/scientificamerican0923-86<\/section>\n[\/vc_column_text][vc_column_text]\u00a9 2023 SCIENTIFIC AMERICAN, A DIVISION OF SPRINGER NATURE AMERICA, INC.[\/vc_column_text][vc_column_text]<\/p>\n<h3>About the Author(s)<\/h3>\n<p><p><strong>Josh Fischman<\/strong>\u00a0is a senior editor at\u00a0<em>Scientific American<\/em>\u00a0who covers medicine, biology and science policy.\u00a0He has written and edited about science and health for\u00a0<em>Discover<\/em>,\u00a0<em>Science<\/em>,\u00a0<em>Earth<\/em>, and\u00a0<em>U.S. News &amp; World Report.<\/em>\u00a0<a href=\"https:\/\/twitter.com\/jfischman\" target=\"_blank\" rel=\"noopener\">Follow Josh Fischman on Twitter.<\/a><\/p>\n[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243; css=&#8221;.vc_custom_1538657003956{padding-top: 0px !important;padding-bottom: 0px !important;}&#8221;][vc_custom_heading text=&#8221;ISSUES&#8221; font_container=&#8221;tag:h3|font_size:12px|text_align:left|color:%23333333|line_height:18px&#8221; use_theme_fonts=&#8221;yes&#8221; el_class=&#8221;titlewidget&#8221;][vc_column_text el_class=&#8221;columnflex&#8221; css=&#8221;.vc_custom_1664404002021{margin-bottom: 40px !important;}&#8221;]<p><a href=\"\/science-connect-october-2023\/\">October 2023<\/a><\/p>\r\n<p><a href=\"\/science-connect-september-2023\/\">September 2023<\/a><\/p>\r\n<p><a href=\"\/science-connect-august-2023\/\">August 2023<\/a><\/p>[\/vc_column_text][vc_custom_heading text=&#8221;OTHER ARTICLES IN THIS ISSUE&#8221; font_container=&#8221;tag:h3|font_size:12px|text_align:left|color:%23333333|line_height:18px&#8221; use_theme_fonts=&#8221;yes&#8221; el_class=&#8221;titlewidget&#8221; css=&#8221;.vc_custom_1674576179369{margin-bottom: 15px !important;}&#8221;][vc_basic_grid post_type=&#8221;post&#8221; max_items=&#8221;-1&#8243; style=&#8221;load-more&#8221; items_per_page=&#8221;4&#8243; element_width=&#8221;12&#8243; orderby=&#8221;rand&#8221; item=&#8221;538&#8243; grid_id=&#8221;vc_gid:1695376300406-57b29906-d9de-3&#8243; taxonomies=&#8221;31&#8243;][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"In inflammatory bowel disease, mental stress can produce two painful responses.<a class=\"more\" href=\"https:\/\/springerhealthplus.nl\/shmigrate\/see-how-stress-affects-inflammatory-bowel-disease\/\">  ...more<\/a>","protected":false},"author":29,"featured_media":2906,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[7],"tags":[30,31],"class_list":{"0":"post-2905","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-science-connect","8":"tag-scientific-american","9":"tag-september-2023"},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - 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